Comfort in Every Bite: The Ultimate Chicken and Stuffing Casserole Recipe

There’s something deeply nostalgic about a casserole. It reminds me of chilly nights in my grandmother’s kitchen—where the scent of roasted chicken mingled with buttery stuffing and everyone gathered around for second helpings. This chicken and stuffing casserole recipe is more than just a dish; it’s a comforting memory baked into a golden, delicious pan.

Whether you’re cooking for a cozy weeknight dinner or prepping ahead for a potluck, this American classic is a lifesaver. It’s hearty, flavorful, and satisfies both the summer cook who doesn’t want to spend hours at the stove and the winter soul craving warmth. Let’s dive into a dish that’s become a staple in my kitchen—and will soon become one in yours.

Why You’ll Love This Chicken and Stuffing Casserole Recipe

Fast and easy prep – 10 minutes is all it takes to put it together.
Flexible ingredients – Great for using up leftover chicken or turkey.
Make-ahead friendly – Perfect for meal planning or freezing.
Crowd-pleaser – Even picky eaters ask for seconds!

This chicken and stuffing casserole recipe is the perfect balance of creamy, savory chicken and tender, buttery stuffing, all baked until golden on top.

Ingredients You’ll Need

Here’s what goes into this flavorful casserole. Most of these ingredients are pantry staples, making it ideal for a quick and satisfying dinner.

For the Filling:

2 cups cooked chicken, shredded or cubed
1 can (10.5 oz) cream of chicken soup
1/2 cup sour cream
1/4 cup milk
1/2 cup diced onion
1/2 cup diced celery
1/2 teaspoon garlic powder
Salt and pepper, to taste

For the Stuffing Topping:

1 box (6 oz) stuffing mix (chicken or herb-flavored)
1 1/2 cups chicken broth or water
3 tablespoons unsalted butter

💡 Tip: You can swap the stuffing mix for homemade if you’re feeling ambitious. Use day-old bread, sautéed onion, celery, herbs, and a splash of broth.

Step-by-Step Instructions

🕐 Prep Time: 10 minutes

🔥 Cook Time: 30-35 minutes

🍽 Total Time: 45 minutes

👨‍👩‍👧‍👦 Servings: 5

1. Preheat and Prep

Preheat your oven to 375°F (190°C). Lightly grease a 9×13-inch baking dish or casserole pan. This helps prevent sticking and ensures easy cleanup.

2. Make the Creamy Chicken Base

In a large bowl, mix together the cream of chicken soup, sour cream, milk, garlic powder, salt, and pepper. Stir until smooth. Fold in the cooked chicken, diced onion, and celery.

Pour this mixture into your prepared baking dish and spread it evenly.

3. Prepare the Stuffing Topping

In a medium saucepan, bring chicken broth and butter to a boil. Remove from heat and stir in the stuffing mix until all the liquid is absorbed. Let it sit for 5 minutes to fluff up.

Spread the stuffing over the chicken mixture in the dish.

4. Bake

Bake uncovered for 30 to 35 minutes, or until the top is golden brown and the filling is bubbling around the edges.

5. Cool and Serve

Let the casserole sit for 5-10 minutes before serving. This helps the layers settle and makes it easier to serve.

Variations & Substitutions

Turkey instead of chicken: A perfect post-holiday leftover solution!
Add vegetables: Mix in frozen peas, corn, or chopped green beans for extra nutrition.
Cheesy twist: Sprinkle shredded cheddar or mozzarella between the chicken and stuffing layers.
Low-sodium: Use low-sodium soup and broth for a healthier version.

Make Ahead & Freezing Tips

This casserole is very freezer-friendly!

To Make Ahead:

Assemble the casserole up to a day in advance, cover tightly, and refrigerate. When ready to bake, add 5 extra minutes to the cook time if baking from chilled.

To Freeze:

Wrap the unbaked casserole tightly in foil and freeze for up to 2 months. Thaw overnight in the refrigerator before baking.

Serving Suggestions

This chicken and stuffing casserole is a complete meal on its own, but if you want to round it out, try these simple pairings:

Green beans almondine for a fresh crunch
Honey-glazed carrots for a touch of sweetness
Cranberry sauce for a tangy holiday flair
Garden salad with vinaigrette for lightness

Frequently Asked Questions

Can I use rotisserie chicken?

Absolutely! It’s a great time-saver and adds wonderful flavor.

What’s the best way to reheat leftovers?

Reheat in the oven at 350°F for 15–20 minutes or microwave individual servings for 2–3 minutes.

Is this casserole gluten-free?

Not as written, but you can substitute gluten-free stuffing mix and cream of chicken soup for a gluten-free version.

A Dish for All Seasons

This dish isn’t just cozy enough for winter—it’s light enough for summer too! Serve it with a crisp salad and iced tea in warmer months or pair it with roasted vegetables and warm cider in the colder seasons.

A Family Favorite That Never Disappoints

Every time I serve this chicken and stuffing casserole recipe, the pan comes back empty. The creamy chicken base with a buttery stuffing crown creates the ultimate comfort food harmony. It’s soul-satisfying, easy to make, and versatile enough for any season or occasion.

If you’re new to casseroles or just looking to bring some old-fashioned love back to the dinner table, this recipe is the one to bookmark. Try it once, and I promise—it’ll become a favorite.

Have You Tried This Recipe?

I’d love to hear how it turned out for you! Share your version of this chicken and stuffing casserole in the comments below. Did you add a twist or stick to the classic? Snap a photo and tag me—because your kitchen creations inspire me just as much as grandma’s did.

1 Best Chicken and Stuffing Casserole Recipe for Busy Families